Pyridoxamine dihydrochloride
CAS No. 524-36-7
Pyridoxamine dihydrochloride ( Pyridorin | Pyridoxylamine Dihydrochloride )
产品货号. M19616 CAS No. 524-36-7
Pyridoxamine DiHClide 是一种维生素 B6 的盐酸盐。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 500MG | ¥340 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Pyridoxamine dihydrochloride
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Pyridoxamine DiHClide 是一种维生素 B6 的盐酸盐。
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产品描述Pyridoxamine Dihydrochloride is a hydrochloride salt of one form of vitamin B6.(In Vitro):Pyridoxylamine (PM), a member of the B6 vitamer family, is a potent scavenger of reactive carbonyls, inhibiting the late stages of glycation reactions that lead to AGE formation.(In Vivo):Pyridoxylamine limits the formation of CML and CEL and cross-linking in skin collagen and, ultimately inhibits the development of nephropathy in STZ-diabetic rats. Pyridoxylamine does not appear to function as an antioxidant since it does not prevent lipid peroxidation reactions. At the same time, it does prevent protein modification by products of lipid peroxidation, including inhibiting formation of malondialdehyde and 4-hydroxynonenal adducts on protein in Zucker rats in vivo.
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体外实验Pyridoxylamine (PM), a member of the B6 vitamer family, is a potent scavenger of reactive carbonyls, inhibiting the late stages of glycation reactions that lead to AGE formation.
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体内实验Pyridoxylamine limits the formation of CML and CEL and cross-linking in skin collagen and, ultimately inhibits the development of nephropathy in STZ-diabetic rats. Pyridoxylamine does not appear to function as an antioxidant since it does not prevent lipid peroxidation reactions. At the same time, it does prevent protein modification by products of lipid peroxidation, including inhibiting formation of malondialdehyde and 4-hydroxynonenal adducts on protein in Zucker rats in vivo.
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同义词Pyridorin | Pyridoxylamine Dihydrochloride
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通路Others
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靶点Other Targets
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受体Others
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研究领域Neurological Disease
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适应症Schizophrenia
化学信息
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CAS Number524-36-7
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分子量241.12
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分子式C8H14Cl2N2O2
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纯度>98% (HPLC)
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溶解度DMSO:10 mM
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SMILESCl.Cl.Cc1ncc(CO)c(CN)c1O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Adrover M et al. The pyridoxamine action on Amadori compounds: A reexamination of its scavenging capacity and chelating effect. Bioorg Med Chem. 2008 May 15;16(10):5557-69.
产品手册
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